Change in Serum Lipid Hydroperoxides in Thermal Injury
1997 年 23 巻 3 号 p. 139-143
詳細
1997 年 23 巻 3 号 p. 139-143
The concentration of serum lipid hydroperoxides of male rats of the Wistar strain that had received thermal injury on their backs was measured by the hemoglobin-methylene blue (Hb-MB) method. The concentration increased significantly 0.5h after the injury, was higher than that of the normal level until 5h, and decreased to the normal concentration by 7h after the injury. The lipid peroxide level measured by the thiobarbituric acid (TBA) method increased up to 5h after the injury, and then maintained at a higher level than normal for 48h. Thus, the measurement of the total concentration of serum lipid hydroperoxides by the Hb-MB method is useful to detect lipid peroxidation in the early period after the injury, and serum lipid peroxide level measured by the TBA method may reflect the progress of systemic dysfunction.
