Blood Pyridine Nucleotide Levels Reflect Niacin Equivalent Intake in Humans
1987 年 3 巻 1 号 p. 37-45
詳細
1987 年 3 巻 1 号 p. 37-45
The relationship between the blood NAD and NADP levels and the niacin equivalent intake was investigated using women students. The daily niacin equivalent intake was 151±64μmol (18.5±7.5mg in terms of nicotinamide, mean±SD). The blood NAD and NADP levels were 34.7±7.0 and 19.3±2.3nmol/ml whole blood, respectively. The blood NAD level was proportional to the blood NADP level. Both blood levels were also proportional to the hemoglobin content, and the NAD and NADP levels per g hemoglobin were 233.7±44.7 and 156.3±25.5nmol. The blood NAD and NADP levels increased with an increase in the niacin equivalent intake. From these results, it is concluded that the blood total pyridine nucleotide level (NAD+NADP) reflects the niacin equivalent intake. Accordingly, the blood pyridine nucleotide level may be useful as an index for niacin nutrition in humans.
