Aminopeptidase Activity of Dinuclear Zinc Complexes and Dinuclear Magnesium Complexes

Abstract

Dinuclear zinc complexes showed aminopeptidase activity, while dinuclear magnesium complexes did not. The reason for the difference is discussed based on the Density Functional Theory (DFT). In the zinc complex, a chelating arm is expected to work as a general base catalyst, while in the magnesium complex, the arm cannot work as a general base catalyst.