Ha Beads for Bone Regeneration

Kay TERAOKA; Yoshiyuki YOKOGAWA; Tetsuya KAMEYAMA

doi:10.14852/jcersjsuppl.112.0.S863.0

Journal of the Ceramic Society of Japan, Supplement 112-1, PacRim5 Special Issue

Session ID : 11

DOI https://doi.org/10.14852/jcersjsuppl.112.0.S863.0

Conference information

Host: The Ceramic Society of Japan

Co-host: Iketani Science and Technology Foundation, International Ceramic Federation, Commemorative Organization for the Japan World Exposition '70, The American Ceramic Society, The Australasian Ceramic Society, The Chinese Ceramic Society, The Korean Ceramic Society, Joint Research Consortium of Synergy Ceramics/Fine Ceramics Research Association, Nanotechnology Researchers Network Center of Japan, The Special Coordination Funds for Promoting Science and Technology, Japan National Tourist Organization, Aichi Prefectural Government, CASIO SCIENCE PROMOTION FOUNDATION, DAIKO FOUNDATION, Nagoya Convention and Visitors Bureau, The Asahi Glass Foundation, The Kao Foundation For Arts And Sciences, The Murata Science Foundation, The Ogasawara Foundation for the Promotion of Science & Engineering, ASAHI GLASS CO., LTD. Research Center, CENTRAL GLASS CO., LTD., ELECTRIC GLASS INDUSTRY ASSOCIATION OF JAPAN (EGAJ), Hattori Company, Ltd., Hitachi Research Laboratory, Hitachi, Ltd., HOYA CORPORATION, INAX Corporation, ITOCHU CERATECH CORP., Japan Cement Association, KYOCERA Corporation, KYUSHU REFRACTORIES CO., LTD., MINO CERAMIC CO., LTD., Murata Manufacturing Co., Ltd., NGK INSULATORS LTD., NGK SPARK PLUG CO., LTD., NICHIAS Corporation, NIKKO COMPANY, Nippon Electric Glass Co., Ltd., Nippon Sheet Glass Co., Ltd., NORITAKE CO., LIMITED, Tokuyama Corporation, TOTO LTD.

Notes

Ha Beads for Bone Regeneration

Kay TERAOKA, Yoshiyuki YOKOGAWA, Tetsuya KAMEYAMA

Author information

Keywords: Bone regeneration, Hydroxyapatite, Porous ceramics

CONFERENCE PROCEEDINGS FREE ACCESS

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Abstract

We are trying to fabricate porous grafts with an optimum macropore network for bone regeneration by integrating hydroxyapatite (HA) tiny units. In this study, φ1 mm spherical HA ceramics with a φ300 μm through-hole (HA beads) were prepared as a model of the unit. By integrating the HA beads, the through-holes could be connected through gaps between the HA beads, thus constructing an interconnected macropore network. Micro X-ray CT analysis of the integrated HA beads proved that the through-holes and the gaps produced an interconnected network. The macro-porosity of the integrated beads was 47.7±1.9%. Bone regeneration in the macropore network was evaluated by an animal test. After 7 days, favorable developments for bone repair were confirmed in the macropore network. This result showed that the HA beads can be the minimum unit to construct an effective macroporous graft for bone regeneration.

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