SICE Journal of Control, Measurement, and System Integration
Online ISSN : 1884-9970
Print ISSN : 1882-4889
ISSN-L : 1882-4889
CONTRIBUTED PAPERS
Model of Gut Absorption from Carbohydrates with Maximum Rate of Exogenous Glucose Appearance in Type 1 Diabetes
Claudia Cecilia YAMAMOTO NOGUCHIShogo HASHIMOTOEiko FURUTANIShoichiro SUMI
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2016 Volume 9 Issue 5 Pages 201-206

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Abstract

An accurate mathematical representation of the impact of carbohydrates on postprandial glucose-insulin metabolism in type 1 diabetes (T1D) is essential for the development of model-based diabetes-related technologies. In this study, the physiological representation of a previous model of gut absorption from carbohydrates is enhanced by including a maximum rate of exogenous glucose appearance as observed in clinical studies in the literature. Simulation results for the same four representative carbohydrate-rich foods with varying glycemic index values as in our previous study, in addition to a sugary beverage, show that the postprandial glycemic excursion relates more closely to clinical data of postprandial glycemic excursion in patients with T1D.

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© 2016 The Society of Instrument and Control Engineers
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