Multinodular and vacuolating neuronal tumor of the cerebrumの長期経過と文献的考察

山澤 恵理香; 大野 誠; 里見 介史; 吉田 朗彦; 宮北 康二; 高橋 雅道; 浅野目 卓; 里見 奈都子; 成田 善孝

doi:10.7887/jcns.28.27

CASE REPORTS

Longitudinal Follow-up of a Case of Multinodular and Vacuolating Neuronal Tumor of the Cerebrum and Review of the Literature

Erika Yamazawa, Makoto Ohno, Kaishi Satomi, Akihiko Yoshida, Yasuji Miyakita, Masamichi Takahashi, Taku Asanome, Natsuko Satomi, Yoshitaka Narita

Author information

Erika Yamazawa
Department of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital
Makoto Ohno
Department of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital
Kaishi Satomi
Department of Pathology and Clinical Laboratories, National Cancer Center Hospital
Akihiko Yoshida
Department of Pathology and Clinical Laboratories, National Cancer Center Hospital
Yasuji Miyakita
Department of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital
Masamichi Takahashi
Department of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital
Taku Asanome
Department of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital
Natsuko Satomi
Department of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital
Yoshitaka Narita
Department of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital

Keywords: multinodular and vacuolating neuronal tumor of the cerebrum, MVNT, multinodular, MAP kinase

JOURNAL OPEN ACCESS

2019 Volume 28 Issue 1 Pages 27-32

DOI https://doi.org/10.7887/jcns.28.27

Details

Abstract

Multinodular and vacuolating neuronal tumor of the cerebrum (MVNT) is a relatively new tumor classification. There are only a few reports of long-term prognosis for MVNTs. Here we report a 5-year follow-up of our case of MVNT with no recurrence after surgery. We also summarize and discuss the literature for 31 other cases. Median age was 41 years, and there was no sex disparity. In around half of the cases, nodules were visible not only by examination of the pathological tissue but also on MRI. In most symptomatic epilepsy improves with surgery. Thus far no malignant transformation of MVNT has been reported, indicating a good prognosis.

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