2018 Volume 71 Issue 5 Pages 216-221
A 38-year-old male with ulcerative colitis (UC) since 28 years of age visited our institution in July 2008 complaining of right lower abdominal pain. Physical and radiographic examinations indicated acute appendicitis. Because he did not wish to undergo surgery, conservative treatment was given. Four months later, he suffered from right abdominal and back pain.
Abdominal CT and MRI scans revealed a solid lobulated tumor, 7×5 cm in diameter, in the ileocecal region with right hydronephroureter. Colonoscopic examination demonstrated findings compatible with mild ulcerative colitis and extrinsic compression of the cecum. The orifice of the appendix was not identified. Endoscopic ultrasonography revealed an isoand hypo-echoic extramural tumor with irregularity of the muscularis propria in the cecum. The diagnosis of appendiceal carcinoma invading the cecum and right ureter was established, and he underwent right hemicolectomy. Histopathological examination revealed adenosquamous carcinoma of the appendix (pT4b, pN2 (5/29), cM0, fStage IIIb). To our knowledge, this is the first reported case of adenosquamous carcinoma of the appendix in association with ulcerative colitis.
