Journal of Epidemiology
Online ISSN : 1349-9092
Print ISSN : 0917-5040
ISSN-L : 0917-5040
Original Article
Descriptive Epidemiology of Prion Disease in Japan: 1999–2012
Yosikazu NakamauraRyusuke AeIchiro TakumiNobuo SanjoTetsuyuki KitamotoMasahito YamadaHidehiro Mizusawa
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2015 Volume 25 Issue 1 Pages 8-14


Background: Epidemiologic features of prion diseases in Japan, in particular morbidity and mortality, have not been clarified.
Methods: Since 1999, the Research Committee has been conducting surveillance of prion diseases, and the surveillance data were used to assess incident cases of prion diseases. For the observation of fatal cases, vital statistics were used.
Results: Both incidence and mortality rates of prion diseases increased during the 2000s in Japan. However, this increase was observed only in relatively old age groups.
Conclusions: The increased number of patients among old age groups might be due to increased recognition of the diseases. If so, the number of cases should plateau in the near future.

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© 2014 Yosikazu Nakamaura et al. This is an open access article distributed under the terms of Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
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