Article ID: JE20180262
Background: Some Okinawan vegetables have been reported to have anti-diabetic activity; however, no prospective cohort study has clarified whether Okinawan vegetables are associated with a risk of type 2 diabetes. This study aimed to determine the association between consumption of Okinawan vegetables and risk of type 2 diabetes through a large-scale, population-based, prospective study in Japan.
Methods: We examined 10,732 participants (4,714 men and 6,018 women) aged 45-74 years who resided in Okinawa. Participants were asked to answer a 147-item food frequency questionnaire. We calculated the overall amount of Okinawan vegetables consumed and the amount of 7 specific kinds of Okinawan vegetables consumed. The odds ratios (ORs) for self-reported type 2 diabetes during 5 years of follow-up were estimated via multivariate logistic regression analysis.
Results: During the 5-year period, 216 new cases (123 men and 93 women) of type 2 diabetes were reported. Comparing the highest tertile to the lowest tertile of intake, the overall amount of Okinawan vegetables consumed was not associated with risk of type 2 diabetes in men (OR=1.22, 95% confidence interval [CI]=0.74-2.01, p-trend=0.53) or in women (OR=0.96, 95% CI=0.57-1.62, p-trend=0.89). The consumption of 7 specific kinds of Okinawan vegetables was also not associated with the risk of type 2 diabetes.
Conclusions: The consumption of total Okinawan vegetables was not associated with the risk of type 2 diabetes.