1995 年 5 巻 2 号 p. 95-98
A matched case control study on MRSA urinary tract infection was carried out. The purpose of our study was to evaluate the effect of the use of antibiotics, the use of the third generation cephems, the hypoalbuminemia and the indwelling of catheter on the occurrence of MRSA urinary tract infection among the elderly. From April 1991 to March 1994, there were 8 inpatients who were suffered from MRSA urinary tract infection, which were used as cases. The twenty four age-and ADL-matched inpatients with non-MRSA urinary tract infection, three controls per case, were used as controls. Compared to the non-MRSA patients, the MRSA patients had a larger amount of antibiotics prior to the bacterial culture (1.3±0.9 vs 0.3±0.6, mean±SD, p<0.05). The third generation cephems were more commonly used in the MRSA patients than in the non-MRSA patients (50.0% vs 4.2%, p<0.05). The level of serum albumin was significantly lower in the MRSA patients than in the non-MRSA patients (3.4±0.6 vs 4.0±0.4 g/dl, p<0.05). Even after controlling confounding factor such as hypoalbuminemia, the use of the third generation cephems was a risk for MRSA urinary tract infection among the elderly (OR: 3.37, 95% Cl : 1.11-10.28). In the elderly, use of the third generation cephems seems to be an important risk factor for MRSA urinary tract infection. J Epidemiol, 1995; 5 : 95-98.