Journal of Epidemiology
Online ISSN : 1349-9092
Print ISSN : 0917-5040
ISSN-L : 0917-5040
Relationship of Serum Cholesterols and Vitamin E to Depressive Status in the Elderly
Hiroshi ShibataShu KumagaiShuichiro WatanabeTakao Suzuki
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1999 Volume 9 Issue 4 Pages 261-267

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Abstract

Various relationships of serum cholesterols and a-tocopherol in the blood to depressive status as assessed by a short version of the Geriatric Depression Score (GDS) were cross-sectionally and longitudinally investigated in the elderly using multivariate analysis. Subjects comprised 504 residents (195 men and 309 women) aged 65 years and over in a rural community. Neither cholesterols nor a-tocopherol significantly related to depressive status in either sex, adjusted for age and educational attainment in cross-sectional analysis. However, both total cholesterol and a -tocopherol at baseline significantly prevented a 4-year longitudinal progression of depressive status in men alone, adjusted for age, education, and the GDS score at baseline. LDL+VLDL cholesterol related in the same fashion as total cholesterol, whereas HDL cholesterol did not significantly relate to the progression of depressive status. J Epidemiol, 1999 ; 9 : 261-267.

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