A Simple Flow Injection Assay of Ca(II) in Mineral Supplement Using Mg(II)-EDTA Original Paper

Kwuanjit Manee-on; Somchai Lapanantnoppakhun; Jaroon Jakmunee; Kate Grudpan

doi:10.24688/jfia.22.1_9

A Simple Flow Injection Assay of Ca(II) in Mineral Supplement Using Mg(II)-EDTA

Original Paper

Kwuanjit Manee-on, Somchai Lapanantnoppakhun, Jaroon Jakmunee, Kate Grudpan

Author information

JOURNAL FREE ACCESS

2005 Volume 22 Issue 1 Pages 9-

DOI https://doi.org/10.24688/jfia.22.1_9

Details

Abstract

A new concept for a simple FI assay of Ca(II) employing a replacement reaction of Mg(II)-EDTA by Ca(II) in the present of Eriochrome Black T (EBT) is proposed. The released magnesium reacts with EBT. FI peak due to absorbance change of Mg(II)-EBT is proportional to Ca(II) concentration. Even with such a very simple FI set up, a through-put of 200 injections/h can be achieved. The procedure was applied to assay Ca(II) in mineral supplement samples. The results obtained agreed well with that of the British Pharmacopoeia titration method.

Corresponding author

Register with J-STAGE for free!