Abstract
The development of audiogenic seizure following sound stimulation (12KC/S, 120phone) was studied using rats each of which underwent 5 tests.Sixteen normal rats tested showed no abnormal behavior.
Seventy-five times of observations of 15 rats with bilateral otitis media showed a typical tonic-clonic convulsion in 53.3%, a convulsive running in 29.3%, a circular running in 5.3%, a turning in 4% and no pathologic behaviour in 8%.
Seven cases of unilateral otitis media showed a trend of circular running or convulsive running to the non-affected side without eliciting typical heavy seizures.
The acoustic stimulation was not effective in all cases after bilateral labyrinthectomy. It seems obvious that audiogenic seizures are influenced by the peripheral auditory organ and the otitis media is considered as one of inducing causes of the seizures.
