One hundred and three surgical cases of carcinoma of the maxillary sinus, were examined and the following results were obtained through the clinical observation and the pathological investi-gation.
(1) Nasal obstruction, nasal hyperdischarge, dentalache and swelling of the cheek, etc. had been noticed as the initial symptoms, but those former three symptoms were not characteristic to this disease;
(2) As the type of cancer multiplication the so-called retro-growth type had been most fre-quently observed.
(3) Because of these two aforesaid facts, over 70% of the cases were not diagnosed correctly at the first examination.
(4) Consequently, the prognosis became unfavorable.
(5) No significant relationship was noticed between the histological diagnosis and the prog-nosis, however, a definite relation was found between the pleomorphism of cancer tissue and the prognosis.
(6) Prognosis was considered to be unfavorable in the cases which presented the varied histo-logical pictures, especially so in those cases which presented these pictures due to Tauchi's so-called atypical adenocarcinoma.
(7) Some considerations were made on the histological picture of the parenchyma and the stroma as well as on the correlation between the two and a histological standard is presented by the author, for the purpose of grading the malignancy of cancer tissue.
As stated above, it may be concluded that, in order to make an early diagnosis and treatment possible, the attention must be paid to the atypical symptoms, and that both the pleomorphism of cancer tissue and the type of cancer growth have influence on the prognosis of the disease.