骨面皮膚移植に関する組織学的研究

抄録

Histological studies of 133 skin grafts in bulla ossea of rabbits were made as one of the fundomentaluts dies of tympanoplasty. The examination was done on 1st, 2nd, 3rd, 5th, 8th, 15th, and 30th postoperative day. The results were as follows:
New epithelium was regenerated under the degenerated old grafts on 3rd and 5th. day. The epithelienr was thiekened after 8th day. Theepithelialization was disturbed by infection, excessive pressure, dryness and insufficient immobilization of the grafts.
When mucus membrane was prsent, cyst formation was frequent and the grafts were scarcely taken, On the periosteum, the grefts were easily taken and epithelialization was safisfactory. On the bone without periosteum, the grafts were difficult to be taken and epithelialization was also disturbed.
When the bone was injured prier to the graft, thick layer of granulation tissue was seen between the skin and bone. Regeneration of the bone was seen on 5th day but organization of the bore fissue was not seen even on 30th day.
Thick grafts contained many hair follicles and sebaceous glands which became at rophied aad formed vacuoles later. There fore, thin grafts were thonght to be better than thick ones.