日本耳鼻咽喉科学会会報
Online ISSN : 1883-0854
Print ISSN : 0030-6622
ISSN-L : 0030-6622
内服卵白リゾチームの血液•副鼻腔組織への移行とリゾチーム濃度について
石田 稔松永 亨
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ジャーナル フリー

1984 年 87 巻 12 号 p. 1678-1683

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Partitioning of egg-white lysozyme between the serum and paranasal tissue was investigated using the ELISA method.
1) Egg-white lysozyme was detected in the paranasal tissues of 7 of 8 subjects given exogenous lysozyme reached a peak concentration in the serum in 60 minutes, whereas, 90 minutes was required to reach peak concentrations in the paranasal tissues.
2) Antibodies against egg-white lysozyme were detected in the serum of 4 of 5 subjects given exogenous lysozyme.
3) Differences in serum concentrations of lysozyme between subjects given exogenous lysozyme and subjects non-receiving lysozyme were not significant.
However, lysozyme concentrations in the paranasal tissues of all subjects receiving exogenous lysozyme were higher than in subjects not receiving an exogenous source of the enzyme.

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