EPSTEIN-BARR VIRUS (EBV) RECEPTORS ON THREE EBV GENOME-POSITIVE EPITHELIAL HYBRID CELLS

Abstract

The authors have measured the relative number of Epstein-Barr virus (EBV) receptors on the surface of A2L/AH, NPC-KT, D98/HR-1, Raji, and P3HR-1 cells using an absorption index. It was determined that similar amounts of P3HR-1 or NPC-KT EBV can attach to D98/HR-1 cells, but that only P3HR-1 EBV can attach to NPC-KT cells. Both P3HR-1 and NPC-KT EBVs adsorb to Raji cells to a similar degree and to a greater level than either epithelial cells (D98/HR-1 and NPC-KT). Neither P3HR-1 or NPC-KT EBV adsorb to A2L/AH and P3HR-1 cells. The results suggest that there may be differences in the receptors for P3HR-1 and NPC-KT EBVs.