A 48-year-old man seen for painless anterior neck and bilateral subauricular masses was found in computed tomography (CT) to have a ring-enhanced cystic anterior neck lesion containing a small calcification. Subauricular masses were positive in both fluorodeoxyglucose positron emission tomography (FDG-PET) and 99mTc-pertechnetate scintigraphy showing hypo- and hyperintensity in T1- and T2-weighted magnetic resonance imaging (MRI). Based on a preoperative diagnosis of thyroglossal duct carcinoma, not a benign cyst, associated with Warthin’s parotid glands tumors, not lymph node metastasis, the man underwent resection of the masses. Histopathologically surgical specimens confirmed our preoperative diagnosis. The man’s postoperative clinical course was uneventful and he remains currently disease-free in the 29 months after surgery.