臨床
放射線単独療法が奏効した下顎骨原発腺様囊胞癌例
2020 年 113 巻 12 号 p. 815-819
詳細
2020 年 113 巻 12 号 p. 815-819
Adenoid cystic carcinoma (ACC) accounts for approximately 1% of all cases of head and neck carcinoma, and ACC of the jaw has rarely been reported. Herein, we report a case of ACC of the mandible which responded well to radiation therapy alone.
An 85-year-old woman presented to us with swelling of the mandible and hypoesthesia extending from the lower lip to the chin. Computed tomography (CT) revealed destruction of the entire mandibular bone. Biopsy of the mandible revealed ACC with a cribriform pattern. Whole-body examination revealed metastasis to the clavicle, sternum, rib, and iliac bone. Considering the patient’s age and her wishes, we selected palliative care, namely, radiation therapy alone, with short-term hospital admission.
After the treatment, the FGD accumulation in the mandible could no longer be seen on positron emission tomography-computed tomography (PET-CT), and the destruction of the mandible had improved.
Usually, patients with ACC are treated by surgery and postoperative chemotherapy. Radiotherapy alone is selected for patients with advanced disease or on account of the less favorable background factors of the patients. The reported 5-year local control rate in response to radiotherapy alone is about 50%, and the treatment was effective in this case.
