Trilafon and Polaramine were concomitantly used on 31 patients with Ménière's disease or conditions exhibiting symptoms similar to Ménière's disease. The results were as follows:
1) The combined use of the prugs was markedly effective in 9 patients, effective in 11 patients, somewhat effective in 5 patients, and not effective in 6 patients.
2) Subjective symptoms such as nausea and vertigo were controlled or ameliorated comparatively early in the treatment, however, a long term therapy was required to control tinnitus and dysacousis.
3) The shorter the time interval between onset of the disease and inception of treatment, the better the results of the treatment.
4) Practically no untoward side effects were recognized with the dosage used in this study.
(This paper was presented at the 259th Meeting of the Japanese Society of Otorhinolaryngology held in Kyushu)