Practica Oto-Rhino-Laryngologica
Online ISSN : 1884-4545
Print ISSN : 0032-6313
ISSN-L : 0032-6313
Clinical Evaluation of Dilazep in Patients with Vertigo due to Cerebrovascular Disturbances
Dilazep Alone and Combined with a Minor Tranquilizer
Koji TokumasuEiji SakataAtsushi KomatsuzakiMasahiko YamamotoTamio KameiSetsuko TakemoriYutaka YoshimotoKen Kitamura
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1985 Volume 78 Issue 9 Pages 1991-2006

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Abstract
Vertigo or dizziness in 88 patients with cerebral arteriosclerosis, or following cerebral infarction or hemorrhage, or TIA or RIND was treated with 300mg/day of dilazep hydrochloride orally for 8 weeks.
1) Dilazep alone was given to 34 patients, and subjective improvement was noted in 78.6%, reduction of disturbance of equilibrium in 68.0%, and both subjective and objective improvement in 75.0%.
2) Dilazep plus a minor tranquilizer was given to 54 patients. Subjective improvement was reported in 86.0%, reduction of equilibrium disturbance in 62.5% and both subjective and objective improvement in 81.4%.
3) Minimal side effects, such as abdominal pain, sleep disturbance and or itching skin were noted in only 3.4%.
Dilazep may be considered to be a useful medication for vertigo or dizziness due to cerebral vascular disease.
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