耳鼻咽喉科臨床
Online ISSN : 1884-4545
Print ISSN : 0032-6313
耳鳴に対するTofisopamの臨床効果
市川 恭介服部 康夫中村 賢二
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1989 年 82 巻 1 号 p. 133-138

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Our previous reports dealt with tinnitus and impaired hearing as autonomic dysfunction in the field of otorhinolaryngology. In 46 patients, tinnitus without hearing loss or with impaired hearing of low-pitched sounds was the manifestation of autonomic dysfunction, as diagnosed by Schellong's test and T. M. I. These patients were treated orally with Tofisopam 150mg daily (50mg three times a day), and changes in the severity of tinnitus were monitored. The treatment was markedly effective or somewhat effective in 32 (70%) of the 46 patients. Schellong's test done at intervals of 2 weeks became negative in 70% of the 20 patients. These results indicate that Tofisopam is effective in the treatment of tinnitus.

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