Abstract
The nuclear DNA content of head and neck tumors (57 malignant, 20 benign) was determined by flow cytometory (FC M).
We used fresh specimens and analyzed the ploidy pattern, S phase fraction and G2M phase fraction. Twenty-six of the 57 (45.6%) malignant tumors were aneuploid and all the benign tumors were diploid. Recurrent tumors tended to be aneuploid.
DNA indices of the recurrent tumors were higher than those of the fresh tumors (p<0.01).
The S phase fraction of diploid malignant tumors were larger than that of benign tumors (p<0.001).
There was no difference in the G2M phase fraction between malignant and benign tumors.
