耳鼻咽喉科臨床
Online ISSN : 1884-4545
Print ISSN : 0032-6313
リポPGE1を用いた耳鳴治療
―特に老人性難聴に伴う耳鳴について―
寒川 高男山中 昇藤原 啓次木村 貴昭與田 順一九鬼 清典林 泰弘
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88 巻 (1995) 2 号 p. 257-261

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Severe tinnitus in 32 patients wtih senile deafness was treated with Lipoprostaglandin E1 10μg i. v. once a week. The tinnitus score was significantly decreased from 10 to 3.9±2.4. Slight to marked improvement was recorded in 90.6% of the patients. Early treatment, within 4 weeks of the onset of tinnitus, was more effective than later treatment. There were 4 patterns of improvement. No severe side effect was observed.
The results of this study suggest that Lipoprostaglandin E1 is very useful in the treatment of tinnitus.

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