Polaprezinc is an anti-ulcerative drug that contains zinc. We used this drug for the treatment of 41 taste disorder patients (21 to 76 years). The rates of improvement were 80.0% in drug-induced, 100.0% in zinc deficient, and 62.5% in idiopathic taste disorders. The overall rate of improvement in all patients was 73.2% (30 cases). These results revealed that polaprezinc is useful for taste disorder patients lacking zinc.