Castleman's disease was first reported by Castlemann et al. in 1954 as localized large benign hyperplastic mediastinal lymph nodes histologically characterized by hyperplasia of lymphoid follicles and capillary proliferation with endothelial hyperplasia. In 1972, Keller et al. subsequently divided Castleman's disease into two types according to the pathologic findings: the hyaline-vascular type and the plasma cell type. We report a case of hyaline-vascular type of Castleman's disease in a 29-year-old female.
The patient presented with 11 years history of a large tumor on the right side of her neck. The tumor size had not increasad for 11 years and she had no symptoms except for neck swelling. CT and MRI showed a single mass (60×50×30mm), and laboratory data were within normal ranges. The tumor was surgically resected and histologically identified as a hyaline-vascular type of Castleman's disease. Postoperatively the patient is well with no recurrence for one year.