耳鼻咽喉科臨床
Online ISSN : 1884-4545
Print ISSN : 0032-6313
ISSN-L : 0032-6313
難治性メニエール病に対する内リンパ嚢拡大術の成績
北原 正章後藤 英一郎松岡 浩史
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2005 年 98 巻 1 号 p. 21-25

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This study evaluated the efficacy of endolymphatic sac-expanding surgery in comparison with medical treatment for intractable Meniere's disease. The outcomes of 47 patients with intractable Meniere's disease who underwent endolymphatic sac-expanding surgery were retrospectively compared with those of 22 patients who were offered surgery but preferred to continue medical treatment instead. Age, gender, disease duration, frequency of attacks and stage of hearing before treatment were almost equally distributed in both the surgically and medically treated groups. The outcomes were analyzed according to the 1995 AAO-HNS reporting guidelines. Definitive spells were completely controlled in approximately 90% of cases every year and hearing was improved in approximately 30% of cases for 0.5 to 6 years after surgery. Statistical analysis demonstrated that endolymphatic sac-expanding surgery is superior to medical treatment, at least from the perspective of immediate improvement in the quality of life. However, the proportion of cases showing hearing deterioration increased from 4% to 26% over 6 years after surgery. We would like to emphasize that further effort to improve and avoid deterioration in hearing remains urgent.

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