伝染性単核球症にひきつづき脳炎を併発したと思われる一症例

抄録

Infectious mononucleosis (IM) is commonly seen in adults but rarely in infants and children. A rare case of Epstein-Barr virus (EBV) encephalitis following IM is reported here.
A 15-year old female, suffering from high fever, pain and swelling of the left neck for about 20 days was admitted to our hospital. Various symptoms and signs such as series of those of IM due to initial infection of EBV were observed.
Five days later, a patient became unconsious and accompanied with frequent tonic convulsion. Soon emergent treatments were performed and her condition changed for the better.
In the cerebrospinal fluid, at that time, pleocytosis which was mainly due to lymphocytosis was observed.
As a result, viral infection was strongly suspected. An increased titer of the EBV antibody, which was presence of VCA-IgM and an increase of VCA-IgG, strongly suspected an initial infection of EBV. Thus, Ara-A and s teroid therapy were applyed to this patient. This therapy proved to be effective and she has recovered completely without any after effects.