1991 年 1991 巻 Supplement52 号 p. 8-14
We experienced 549 patients with microtia between 1968 and 1991.
Males distinctly predominated, with sex ratio being 9:5.
Of the 549 patients, the right ear was malformed in 319 and the left in 181, and malformation was bilateral in 49. In almost all patients with microtia, it was associated with congenital aural atresia or high-grade stenosis.
Seven cases of familial microtia were found, in which 3 of the fathers had cup-ears.
About 27% of the patients' mothers had had a cold, threatened spontaneous abortion, toxemia or other complication during their pregnancy.
No obvious genetic or environmental factors in the etiology of microtia were found.