2014 年 25 巻 3 号 p. 157-160
Anserine （beta-alanyl-N-methyl histidine）, which is one of the dipeptides, found in the skeletal muscle and brain of mammals. The muscle tissues of bonito and tuna contain anserine in greater quantities than the muscle tissues of other fish. Bonito and tuna begin swimming the oceans at the age of two years, and swim continuously night and day. Furthermore, when they are in pursuit of a food source, it is said that they reach speeds of 60 kilometers per hour or more. Anserine may have functions to reduce muscle fatigue because of an anti-oxidative effect and buffering capacity due to the presence of an imidazole group. In recent years, we have also found a new healthy function of anserine, which is lowering effect on uric acid value.