治療前および体重増加期に血中leptinとIGF-I濃度を測定したanorexia nervosa患者の1例

抄録

One case of a 17-year-old woman with anorexia nervosa is reported. We measured the concentration of the serum leptin and IGF-I (insulin-like growth factor-I) before and after partial weight recovery. During this period, the serum leptin level was low, but the IGF-I increased as her weight increased. When the percentage of adipose tissue to total body mass is severely low, the serum leptin level, which is widely reported to be a good indicator of recovery from anorexia nervosa, does not accurately reflect the real nutritive state. On the other hand, even in this circumstance we consider IGF-I to be a good indicator.