計量生物学
Online ISSN : 2185-6494
Print ISSN : 0918-4430
ISSN-L : 0918-4430
研究速報
測定誤差のある原爆被爆者からの染色体異常データの解析:
大規模外部情報の利用
中島 栄二大瀧 一夫
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ジャーナル フリー

1995 年 16 巻 1.2 号 p. 19-36

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Overdispersion data of chromosome-aberration rates from atomic-bomb survivors were analyzed by the quasilikelihood/pseudolikelihood (QL/PL) estimating equation method (Breslow 1990). The variance function was composed of two extra-binomial variations: one is an intra-individual correlation, the other is a variation from dosimetry error. This dose-error-variance component was derived using the quasi-structural method (Pierce, Stram, Vaeth and Schafer 1992) that incorporates large-scale external dosimetry information. Using the results of fitting the QL/PL estimating equation, the Wald test revealed that the dose-estimation error is a significant source of overdispersion.

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© 1995 日本計量生物学会
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