計量生物学
Online ISSN : 2185-6494
Print ISSN : 0918-4430
ISSN-L : 0918-4430
無構造仮説群の多重性制御法
長谷川 貴大
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2015 年 36 巻 Special_Issue_2 号 p. S123-S145

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Multiplicity issues are encountered in confirmatory clinical trials with multiple clinical objectives. In order to control the familywise error rate in a clinical trial at a desirable level, a variety of multiplicity adjustment methods are commonly used. In this paper, we focus on the multiplicity testing procedures for non-pre-specified hypothesis ordering consisting of the single-step and data-driven hypothesis ordering, and illustrate them according to the distributional information.

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© 2015 日本計量生物学会
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