Abstract
A 15–year–old subject with hemophilia A who had bumped himself at home and was injected with 1,000,U of factor VIIIgradually developed worsening abdominal pain for which he was seen 10 hours after the injury. Abdominal computed tomography (CT) and echography showed no ascites or worked organ injury. Despite additional 2000 U of factor VIII replacement therapy, his pain worsened and his abdomen become distended. Seen again 16 hours after injury, CT showed massive ascites and hepatic hematoma definitively diagnosed as typeIhepatic injury developing into delayed hepatic rupture of the liver with hemoperitoneum successfully managed with factor VIII and continuous fresh–frozen plasma replacement therapy.