Nihon Gekakei Rengo Gakkaishi (Journal of Japanese College of Surgeons)
Online ISSN : 1882-9112
Print ISSN : 0385-7883
ISSN-L : 0385-7883
Risk Factors of Postoperative Early Tumor Recurrence in Recurrent Cases after Curative Resection for Stage Ⅱ/Ⅲ Colorectal Cancer
Koji NumataHayato WatanabeAya KatoHiroyuki SaekiYasushi RinoMunetaka Masuda
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2019 Volume 44 Issue 5 Pages 865-870

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Abstract

[Objective] To clarify the risk factors associated with early tumor recurrence in recurrent cases after curative resection for Stage Ⅱ/Ⅲ colorectal cancer.

[Methods] A retrospective review was performed of 164 cases of grossly radical colectomy for Stage Ⅱ/Ⅲ colorectal cancer during the period between 2000 and 2016. We divided these cases to two groups (recurrent within one year; group E, and recurrent after a year: group L) and compared the clinicopathological features of the two groups.

[Results] The overall early tumor recurrence rate was 45.1% of the recurrent colorectal cancer (74/164 cases). Univariate analysis identified three factors as risk factors for early tumor recurrence; pathological T4 (pT4), venous invasion, and pN3. Multivariate analysis selected two independent risk factors for early tumor recurrences; pT4 (OR = 1.89, p = 0.038), and pN3 (OR = 5.66, p = 0.029).

[Conclusion] pT4 and pN3 are considered as the risk factors for early tumor recurrence after curative resection for colorectal cancer.

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© 2019 Japanese College of Surgeons
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