Abstract
Adhesion of tissues are carried out by themselves through wound healing processes. The processes are disturbed when there are synthetic materials including adhesives between the tissues. But we have to use cements to fix a tissue with an artificial material, sometimes. Mechanical fixation is main mechanism here. The author can develop adhesives to tooth substrates recently and the mechanism is investigated. Biocompatible monomers promote the interpenetration of monomers into the subsurface of tissues and they are polymerized in situ to form hybrid of tooth substrate and the copolymers. The hybrid can intermediate the tooth with the cured adhesive and the adhesion can take place.
