医薬品情報学
Online ISSN : 1883-423X
Print ISSN : 1345-1464
ISSN-L : 1345-1464
短報
日本人を対象とした食後血糖値上昇に対する難消化性デキストリンの効果: 二重盲検プラセボ対照ランダム化比較試験のメタアナリシス
波多江 崇田中 智啓猪野 彩田内 義彦竹下 治範辰見 明俊濵口 常男
著者情報
ジャーナル フリー

2017 年 18 巻 4 号 p. 289-294

詳細
抄録

Objective: We conducted a meta-analysis on the suppressive effect of resistant maltodextrin on post-prandial blood glucose elevation, which is approved in Japan as food for specified health use, and the following is allowed to be indicated on the label “it is suitable for consumption by those who are concerned about their post-prandial blood glucose levels because the absorption of sugars is abated by the action of dietary fiber (resistant maltodextrin).”
Method: Our literature search covered Ichushi-Web (Japan Medical Abstracts Society), Japan Science and Technology Information Aggregator, Electronic (J-stage), Google Scholar, and PubMed databases and extracted English and Japanese publications on randomized, double-blind, controlled studies comparing resistant maltodextrin and a control in Japanese subjects for the reduction of areas under the blood glucose response curves at 30, 60, and 120 min after eating as an efficacy index.
Result: Among these publications, four articles with a Jadad score (an assessment of the quality of randomized controlled studies) of ≥ 3 were included in the meta-analysis.  Significant inhibitory effects were confirmed from areas under the blood glucose response curves at 30, 60, and 120 min after eating in the meta-analysis that was performed to evaluate the effects of resistant maltodextrin on post-prandial blood glucose elevation in Japanese individuals.
Conclusion: However, we were not able to test for publication bias because the number of extracted publications was small, and thus, additional research and case studies are warranted.

著者関連情報
© 2017 日本医薬品情報学会
前の記事 次の記事
feedback
Top