The Japanese Journal of Gastroenterological Surgery
Online ISSN : 1348-9372
Print ISSN : 0386-9768
ISSN-L : 0386-9768
A Case Report of Duodenal Gastrinoma which Caused Anastomotic Ulcer due to Vagal Gastric Acid Hypersecretion
Hirofumi OtaNobuhisa UedaSeiichi MatsunagaYoshiichi MaeuraEiji AkizukiTakuji SugimotoKazuyoshi Tomita
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1996 Volume 29 Issue 7 Pages 1658-1662

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Abstract

A 50-year-old woman following gastric ulcer underwent resection of the jejunum and distal gastrectomy as an emergency operation for jejunal perforation in August 1992. After the operation, gastrinoma was suspected because the fasting serum gastrin level was 1224 pg/ml and the secretin provocation test was positive. Ultrasonography and CT scanning failed to reveal the presence of any tumor in the pancreatic region. We performed a selective arterial secretin injection test, and confirmed that microgastrinomas were present in the feeding region of gastroduodenal artery. Pancreatoduodenectomy was performed in December 1992. We confirmed the radicality with an intraoperative secretin provocation test, and carried out reconstruction in a manner that preserved the gastric remnant. Although the serum gastrin level remained normal, the anastomotic stoma became stenotic by anastomotic ulcer. Resection of the stenotic part and truncal vagotomy were performed in order to reduce vagal gastric hypersecretion. Recently a stomach-preserving method has been chosen due to the develolpment of the localization method for gastrinomas. When we select the stomach-preserving operation, we should add truncal vogotomy considering the possibility of anastomotic ulcer due to vagal gastric hypersecretion.

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この記事はクリエイティブ・コモンズ [表示 - 非営利 4.0 国際]ライセンスの下に提供されています。
https://creativecommons.org/licenses/by-nc/4.0/deed.ja
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