日本衛生学雑誌
Online ISSN : 1882-6482
Print ISSN : 0021-5082
ISSN-L : 0021-5082
総説
ゼブラフィッシュモデルの環境毒性学研究における有用性
蔣池 勇太松岡 雅人
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ジャーナル フリー

2016 年 71 巻 3 号 p. 227-235

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Recently, a tropical freshwater fish, the zebrafish, has been generally used as a useful model organism in various fields of life science worldwide. The zebrafish model has also been applied to environmental toxicology; however, in Japan, it has not yet become widely used. In this review, we will introduce the biological and historical backgrounds of zebrafish as an animal model and their breeding. We then present the current status of toxicological experiments using zebrafish that were treated with some important environmental contaminants, including cadmium, organic mercury, 2,3,7,8-tetrachlorodibenzo-p-dioxin, and tributyltin. Finally, the future possible application of genetically modified zebrafish to the study of environmental toxicology is discussed.

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© 2016 日本衛生学会
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