2012 Volume 53 Issue 3 Pages 171-176
Injection laryngoplasty is one of the typical remedies used in the treatment of glottal insufficiency. In Japan, silicone, collagen, autologous fat, and calcium phosphate cement have been used as injectable materials. No material, however, has been able to fully satisfy all ideal conditions with respect to biocompatibility, non-absorbency, non-migration, and ready formulation for easy injection.
Hyaluronic acid (HA) is one component of the extracellular matrix that plays a key role in tissue viscosity, shock absorption, wound healing, and space filling. Research into the role of HA in laryngology indicates that it has profound effects on the structure and viscoelasticity of vocal folds.
Injection laryngoplasty using HA was performed on 13 patients with glottal insufficiency. The indications and limitations of injection laryngoplasty using HA were discussed.
1) For augmentation of the vibrating part of the vocal fold, injection laryngoplasty using HA was indicated to be effective.
2) Injection laryngoplasty using HA was indicated to be effective for patients who underwent injection laryngoplasty using other materials and had bad outcomes.
3) Another operative procedure is indicated for medialization of vocal folds.
