Abstract
Myelodysplastic Syndrome (MDS) describes a group of hematological disorders characterized by peripheral cytopenia and dysplastic changes of hematopoietic cells. There are no effective treatments without bone-marrow transplantation which is limited to young patients and the prognosis of MDS is poor due to development of bone-marrow complications or leukemia.
A74-year-oldmale, referred to Asahi University hospital for comprehensive examination of _??_. Because of recurrent periapical infection, dental extraction of _??_ appeared to be the best solution. Past medical history revealed, MDS and drug allergy and pancytopenia (WBC: 1, 130/μl, RBC: 218×104/μl, Plt: 1.9×104/μl). According to his medical doctor's recommendation, perioperative management was focused on prevention and/or avoidance of hemorrhage and infection. Topical application of oxidized cellulose cotton and extreme care during suturing resulted in hemostasis within 1 hour after dental extraction. Telithromycin was selected for post extraction infection control after sensitivity test for this drug more than satisfactory results were attained.
