Abstract
Myelodysplastic syndrome (MDS) includes a group of hematologic malignancies characterized by dysplastic abnormalities of hematopoietic stem cells. An awareness of signs and symptoms related to MDS, such as malaise, pancytopenia, anemia, bleeding tendency, and susceptibility to infection, is essential for safe dental treatment, but there are few reports of infection or bleeding complications caused by dentures in patients with MDS. We report 2 cases of complications caused by ill-fitting dentures. A 73-year-old man was referred to our department because of petechial hemorrhages on the entire palate. Diffuse submucosal petechial hemorrhages caused by an ill-fitting maxillary denture were diagnosed. An 80-year-old woman was referred to our department because of swelling and pain in the right mandibular region. She was given a diagnosis of periostitis of the mandible due to denture-induced stomatitis associated with a red ulcerated lesion beneath the denture. These cases suggested importance of directing attention to prostheses that might cause unexpected complications and to the risk of the acute deterioration of symptoms in patients with MDS.
