Abstract
Dermatomycoses are a common category of fungal infections affecting the skin and subcutaneous tissues. Recent advances in topical and systemic antifungal chemotherapy have provided us with satisfactory results in most of the superficial fungal infections both clinically and mycologically. Despite the efficacy of antifungal agents, however, there are dermatomycoses that do not respond to our current standard regimens of treatment. Factors concerning the treatment-resistance, such as host's underlying conditions and fungal virulence, are discussed in detail.