日本口腔外科学会雑誌
Online ISSN : 2186-1579
Print ISSN : 0021-5163
ISSN-L : 0021-5163
症例報告
顎下部に生じた孤立性線維性腫瘍の1例
杉山 健太郎森川 暁山田 学岩渕 絵美岩渕 博史内山 公男
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2013 年 59 巻 10 号 p. 632-636

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Recently, a growing number of studies have suggested that solitary fibrous tumors (SFTs) occur throughout the body in multiple organs, other than the pleura. Reports on local recurrence and metastasis have proposed that extra-pleural SFTs (including soft-tissue tumors) are medium-grade malignancies among fibroblastic and myofibroblastic tumors according to the World Health Organization tumor classification. We report a case of solitary fibrous tumor in the submandibular region.
Our subject was a 23-year-old woman who presented with a painless swelling in the right side of the submandible. We confirmed the presence of a well-defined, oval tumor (38× 25 mm) in the right side of the submandible on magnetic resonance imaging. T1-weighted images showed uneven low signal intensity, while T2-weighted images showed uneven high signal intensity. Gadolinium-enhanced T1-weighted imaging showed contrast enhancement in a large portion of the tumor. Based on the clinical diagnosis of a benign tumor of the submandibular gland, the tumor was resected with the patient under general anesthesia. Histopathological analysis revealed that the tumor was restricted to the fibrous membrane, with a dense proliferation of spindle/ short-spindle cells. Immunohistochemical staining was positive for CD34 and bcl-2, which confirmed the diagnosis of SFT. Neither recurrence nor metastasis has occurred as of 34 months after surgery.

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© 2013 社団法人 日本口腔外科学会
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