Mesothelioma is a rare neoplasm that arises from the pleura or peritoneum. Although malignant mesothelioma is known to spread hematogenously, causing metastasis to various organs, there have been few reports on oral metastasis. The patient was a 75-year-old man who had an elastic soft mass, measuring 38 × 20 mm, in the right upper jaw gingiva. On biopsy the lesion was histopathologically diagnosed as a malignant pleural mesothelioma with metastasis to the upper jaw. The lesion shrank in response to radiotherapy. We have described a case of malignant pleural mesothelioma arising in the upper jaw gingiva. We discuss the related literature and summarize our findings.
