2018 Volume 64 Issue 8 Pages 475-479
We report a case of rhabdomyosarcoma arising in the buccal region of a 20-year-old male. He was referred to our hospital because of swelling in the right buccal region. Clinical examination showed an elastic hard mass with ulceration measuring 25 × 20 mm in the right buccal region. Magnetic resonance imaging revealed a well-defined mass of high signal intensity on T2-weighted images in the right buccal region. We removed the lesion via an intraoral approach.
Histopathological examination showed that the tumor consisted of the small round and polygonal cells that showed an alveolar structure. Immunohistochemically, the tumor cells exhibited a positive reaction for desmin and myogenin. Based on those findings, the tumor was diagnosed as an alveolar-type rhabdomyosarcoma.
The lesion was classified in group Ⅰ a of the Postsurgical Grouping Classification and stage 1 of the Presurgical Staging Classification according to the Intergroup Rhabdomyosarcoma Study (IRS) classification. Treatment was performed according to the IRS protocol. The patient received chemotherapy with intravenous injection of vincristine, actinomycin, and cyclophosphamide (VAC regimen) and radiotherapy (36 Gy).
There has been no evidence of local recurrence or distant metastasis as of 3 years after surgery.
