日本口腔外科学会雑誌
Online ISSN : 2186-1579
Print ISSN : 0021-5163
ISSN-L : 0021-5163
症例報告
下顎歯肉に限局して初発したCD5陽性びまん性大細胞型B細胞性リンパ腫の1例
宮本 勲小山 知芳木村 康石田 翔高原 利和丹沢 秀樹
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2019 年 65 巻 9 号 p. 582-586

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Diffuse large B-cell lymphoma (DLBCL) is the most common type of non-Hodgkin lymphoma. The T-cell marker CD5 is positive in 5% to 10% of cases of DLBCL. We describe a rare case of CD5-positive DLBCL presenting with swelling of the mandibular gingiva. The patient was a 78-year-old-woman with a chief complaint of swelling of the mandibular gingiva. Biopsy was performed, and the patient was given a diagnosis of DLBCL. Moreover, analysis of the immunophenotype demonstrated that the lymphoma cells expressed CD5. The final diagnosis was CD5-positive DLBCL. The patient was treated with R-CHOP. There have been no signs of recurrence after the chemotherapy.

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