2021 Volume 67 Issue 2 Pages 67-70
Glycogenic acanthosis (GA) is a benign lesion with glycogen-rich keratinocytes, characterized by small, white, slightly raised plaques. GA is frequently detected in the esophagus, and rarely occurs in the oral cavity. We herein report a case of GA in the bilateral buccal mucosa and lower lip of a 14-year-old male. The patient noticed white lesions in the oral cavity 3 months prior to presentation at a nearby dental office, and was then referred to our hospital for further examination. The lesions showed plaque-like thickening of the mucosa, which was whiter than the surrounding mucosa, and were deeply stained with iodine. The lesions were diagnosed as oral GA histopathologically, and the patient has been under observation. In the five years since the first examination, no changes have been observed regarding macroscopic findings and iodine staining assay.
Since GA presenting in the oral cavity is rare, it is necessary to gather more cases to clarify the clinical features of GA in the future.