2021 Volume 67 Issue 4 Pages 243-247
Madelung disease is a benign nontumorigenic disease characterized by multiple and symmetrical unencapsulated adipose tissue deposits on the neck, shoulders and upper extremities. Simultaneous systemic and oral expressions are very rare. We report a case of Madelung disease arising from tongue.
The patient was a 53-year-old man who presented with bilateral swelling of the tongue. The patient had a history of alcoholic hepatitis and depression. MRI showed bilateral mass lesions under the tongue and on the neck. An excisional biopsy was performed on the left-side nodule because of tongue injury caused by accidental biting. The histopathological diagnosis was lipomatosis. Two years have passed since the operation and there has been no recurrence.