A study of blood flow kinetics in a healed wound using the laser doppler flowmeter

Abstract

Measurements of the blood flow kinetics in a healed wound using the laser doppler flowmeter (LDF) and its simultaneous comparative histopathological studies revealed the following interesting results:
1) Blood flow for the nylon suture group showed a recovering tendency just postoperatively, and 5 days later, returned to its quasi-normal range with a significant difference from the Tisseel® adhesion group.
2) Blood flow for the Tisseel® adhesion group showed only half of that for the nylon suture group on the first postoperative day, and then gradually increased to reach that for the latter group on the 6th postoperative day.
3) Histopathological searches revealed that the former group showed a wound healing process a little more retarded than the latter group till the 5th postoperative day.
The above results suggest that the present LDF-blood flowmetry constitutes one of the hopeful means for various kinds of researches in future in that together with its consistency with related histopathological findings, it well reflects the peripheral blood flow kinetics and permits sensitive measurements of the tissue blood flow with delicate variability.